Using mathematics to treat diabetes



                                       
   ...five minutes at a time



Publications

Human bionic pancreas studies

Outpatient Glycemic Control with a Bionic Pancreas in Type 1 Diabetes

New England Journal of Medicine, 2014. PDF

Supplemental online material. PDF




Autonomous and Continuous Adaptation of a Bihormonal Bionic Pancreas in Adults and Adolescents with Type 1 Diabetes.
  

J. Clinical Endocrinology and Metabolism, 2014. PDF

Supplemental online material. PDF


 Blood Glucose Control in Type 1 Diabetes With a Bihormonal Bionic
 Endocrine Pancreas.

 Diabetes Care, 2012. PDF
 
 Supplemental online material. PDF


 A Bihormonal Closed-Loop Artificial Pancreas for Type 1 Diabetes.

 Science Translational Medicine, 2010. PDF

 Supplemental online material. PDF
 



Efficacy Determinants of Subcutaneous Microdose Glucagon During Closed-Loop Control.
J. Diabetes Science and Technology, 2010. PDF (includes appendix)

CGM comparison studies

A Comparative Effectiveness Analysis of Three Continuous Glucose Monitors: The Navigator, G4 Platinum, and Enlite

J. Diabetes Science and Technology, 2014. PDF




Comparative Effectiveness Analysis of Three Continuous Glucose Monitors.

Diabet
es Care, 2013. PDF (includes supplement)



Animal bionic pancreas studies

A Feasibility Study of Bihormonal Closed-Loop Blood Glucose Control Using Dual Subcutaneous Infusion of Insulin and Glucagon in Ambulatory Diabetic Swine.
 
J. Diabetes Science and Technology, 2009. 
PDF

Adaptive Closed-Loop Control Provides Blood-Glucose Regulation Using Dual Subcutaneous Insulin and Glucagon Infusion in Diabetic Swine.
J. Diabetes Science and Technology, 2007. 
PDF

Pharmacodynamics and Stability of Subcutaneously Infused Glucagon in a Type 1 Diabetic Swine Model In Vivo. 
Diabetes Technology and Therapeutics, 2007. 
PDF
Review and commentary

Continuous Glucose Monitoring Awaits Its “Killer App”.
J. Diabetes Science and Technology, 2008. 
PDF